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Neurovascular invasion in bone sarcoma. Which limiting factor to limb salvage ? (about 520 patients)

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Neurovascular invasion in bone sarcoma. Which limiting factor to limb salvage ? (about 520 patients)
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Neurovascular invasion in bone sarcoma. Which limiting factor to limb salvage ? (about 520 patients)

G. Delépine

Hôpital R Poincaré -Oncologic Pediatric unit

Garches



EFORT 2008 Nice 29 au 31 mai 2008



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Material

From 1/1981 To 31 /12/2003

520 sarcomas of limb or girdle.

Average size 13.1 cms.

265 Osteosarcomas

135 chondrosarcomas

130 Ewing’ s sarcoma



Method

 All patients had Xrays and CT scan

 350 NMR

 45 vascular exploration

 Their results were compared to the operative constatations and to histologic findings



Results in osteosarcoma



The artery was not involved



Huge pelvic osteosarcoma

 Resection showed no NV invasion .10 years DFS



Others cases without NV invasion

.

In chondrosarcoma NV invasion is exceptional : 5%



 Sciatic nerve invahided



Neurovascular invasion was not observed in Ewing

 Even in very huge tumors



Conclusions

Neurovascular invasion is too rare to limit significantly limb salvage in bone sarcoma



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